Over 100,000 people are waiting for organ donations in the United States. Many will likely never receive one, since there are so few available. So scientists are turning to pigs for potential alternatives. Their organs are remarkably similar to ours, and scientists are now using CRISPR to modify pigs' DNA to improve transplantation outcomes. But although the field has shown major advances in the last decade, the technique isn't ready yet. Recently, a patient who received a modified pig heart died six weeks after the surgery.
Artist Heather Dewey-Hagborg was intrigued by these recent advances, and looked into humanity's history of modifying the pig over thousands of years for her new gallery exhibit, Hybrid: an Interspecies Opera. For the work, she interviewed scientists and archaeologists and even filmed in a lab that's experimenting with genetically modifying pigs to create more human-compatible organs.
In the resulting documentary, which plays in the exhibit, the words from the scientists she interviewed are transposed into an opera composed by musician Bethany Barrett. Visitors can also find 3D-printed clay pig statues and a timeline of how humans have transformed pigs over ten millennia, thanks to selective breeding.
Dewey-Hagborg sat down with SciFri producer D. Peterschmidt to talk about how the exhibit came together, and how CRISPR could further transform pigs and our relationship to them.
